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Human FLIP, Synthetic Peptide, Invitrogen™

Synthetic Peptide

Manufacturer:  Invitrogen PEP0025

Catalog No. PEP0025


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Description

Description

FLIP Synthetic Peptide, PEP-0025, from Invitrogen.

FLIP (CFLAR) is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian cells. It acts as an inhibitor of TNFRSF6 mediated apoptosis. A proteolytic fragment (p43) is likely retained in the death-inducing signaling complex (DISC) thereby blocking further recruitment and processing of caspase-8 at the complex. Full length and shorter isoforms have been shown either to induce apoptosis or to reduce TNFRSF-triggered apoptosis. Lacks enzymatic (caspase) activity. This peptide corresponds to 19 amino acids near the carboxy terminus of human FLIP.PEP-0025 can be used as a blocking peptide with polyclonal antibody PA5-19899.
Specifications

Specifications

Synthetic Peptide
purified
50μg
Blocking Assay, Control
PBS with 0.1% BSA and 0.02% sodium azide; pH 7.2
Human
RUO
0.02% sodium azide
CFLAR
Blocking Assay, Control
8837
Human
200μg/mL
Liquid
N
PBS
-20°C
Human FLIP
O15519
Peptide
Documents
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