FLT1 Mouse anti-Human, Clone: OTI8G6, lyophilized, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene CF806766

Catalog No. 50-166-7964

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.

Specifications

• Antigen: FLT1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: FLT1
• Format: Lyophilized
• Gene Symbols: FLT1
• Immunogen: Human recombit protein fragment corresponding to amino acids 781-1338 of human FLT1 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human

• Applications: Western Blot
• Clone: OTI8G6
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P17948
• Gene Alias: FLT, FLT-1, VEGFR-1, VEGFR1
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μg
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 2321