FOLR2 Mouse anti-Human, Clone: OTI4G6, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526933
DescriptionFOLR2 is a member of the folate receptor (FOLR) family, and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives, and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins, respectively. Although this protein was originally thought to be specific to placenta, it can also exist in other tissues, and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|BETA-HFR, FBP/PL-1, FR-BETA, FR-P3, FBP, folate receptor beta, folate receptor, beta, folate receptor, fetal/placental, folate-binding protein, fetal/placental, placental folate-binding protein|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 20-221 of FOLR2 produced in E.coli|
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