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FOS Mouse anti-Human, Clone: OTI7D6, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF806977

Catalog No. 50-166-8060


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

FBJ murine osteosarcoma viral oncogene homolog is commonly known as Cellular protooncogene Fos (c-Fos). It belongs to the fos transcription factor family and is encoded by the C-FOS gene located on chromosome 14. c-Fos heterodimerizes with c-Jun to form the Activator Protein -1 (AP-1) transcription factor which regulates transcription of several genes that play an important role in cellular signal transduction, cell proliferation and differentiation. c-Fos has been shown to be phosphorylated by various stimuli including growth factors and insulin at atleast seven different sites. The best known upstream kinase for phosphorylation at Threonine 232 is ERK MAPK which regulates localization of c-Fos to the nucleus and is thus important for c-Fos induced transcriptional activity.
Specifications

Specifications

FOS
Monoclonal
Unconjugated
FOS
Lyophilized
FOS
Full length human recombit protein of human FOS produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin)
OTI7D6
PBS with 8% trehalose and no preservative; pH 7.3
P01100
AP-1, C-FOS, p55
Mouse
IgG1
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
2353
SDS
Documents
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