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FOXL2 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
$145.44 - $572.16
Specifications
| Antigen | FOXL2 |
|---|---|
| Concentration | Lot-Specific |
| Applications | Western Blot |
| Classification | Polyclonal |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
50-199-3300
|
Active Motif
61284 |
10 μL |
Each for $145.44
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50-199-3299
|
Active Motif
61283 |
100 μL |
Each for $572.16
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Description
FOXL2 is a winged helix/forkhead transcription factor that is highly conserved in human, goat, mouse, and certain aquatic species. Given its cross-species conservation, it appears to play a critical role evolutionarily, likely in ovarian differentiation in mammals and in ovarian somatic cell differentiation and in further follicle development and/or maintenance. Immunohistochemical data shows that FOXL2 is a nuclear protein specifically expressed in eyelids and in fetal and adult ovarian follicular cells. It does not undergo any major posttranslational modifications. FOXL2 is also found to be associated with blepharo-phimosis/ptosis/epicanthus inverses syndrome (BPES). There are two forms of BPES. Type I BPES shows eyelid abnormal-ities that are associated with ovarian failure. In type II BPES, only eyelid defects are found. Studies have shown that FOXL2 is expressed in the mesenchyme of developing mouse eyelids and in adult ovarian follicles.Specifications
| FOXL2 | |
| Western Blot | |
| Unconjugated | |
| Rabbit | |
| Human | |
| P58012 | |
| 668 | |
| This FOXL2 antibody was raised against a peptide within the N-terminal region of human FOXL2. | |
| Primary | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| FOXL2 |
| Lot-Specific | |
| Polyclonal | |
| Liquid | |
| RUO | |
| PBS with 30% glycerol and 0.035% sodium azide; pH 7.5 | |
| AU045128; Blepharophimosis; BOS_1244; BPES; BPES1; epicanthus inversus; forkhead box L2; Forkhead box protein L2; forkhead transcription factor FOXL2; forkhead transcription factor L2; Foxl2; LUSTR2; MGC14393; Pfrk; P-Frk; PINTO; Pituitary forkhead factor; POF3; putative transcription factor foxl2 | |
| FOXL2 | |
| IgG | |
| Antigen affinity chromatography | |
| Antibody |
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