FOXP2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 205291AP
DescriptionThis gene encodes a member of the forkhead/winged-helix family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1, also known as autosomal domit speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O15409, P0CF24, P58463|
|CAG repeat protein 44, CAGH44, forkhead box P2, Forkhead box protein P2, FOXP2, SPCH1, TNRC10|
|114142, 500037, 93986|
|Immunoprecipitation, Western Blot|
|FOXP2 Fusion Protein Ag14391|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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