Fra1 Mouse anti-Human, Clone: OTI12F9, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524973
DescriptionThe v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1 and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by a variety of agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers that bind to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. In addition, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun. Different dimers exhibit differential specificity and affinity for AP-1 and CRE sites.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|FOSL1; FRA1; FOS-like antigen 1 ; HGNC:13718; fra-1 ; FOS-like antigen-1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full-length protein expressed in 293T cell transfected with human FOSL1 expression vector|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok