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Invitrogen™ Fractalkine/CX3CL1 Human ELISA Kit Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.

Sandwich ELISA Kit

$487.00

Specifications

Storage Requirements 2°C to 8°C
Assay Sensitivity 300 pg/mL
Assay Range 0.2469-60 ng/mL
Test Time 1 hr. 20 min.
Sample Volume Plasma, 50 μL; Serum, 50 μL; Supernatant, 100 μL
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Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
EHCX3CL1 Non-distribution product as customer accommodation. Available on GSA/VA Contract for Federal Government customers only.
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Invitrogen™
EHCX3CL1
96 Tests
Pack for $487.00
Add to cart
 
Description

Description

The Human Fractalkine/CX3CL1 ELISA quantitates Hu Fractalkine in human serum, plasma, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu Fractalkine. Principle of the method The Human Fractalkine solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

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Specifications

Specifications

2°C to 8°C
0.2469-60 ng/mL
Plasma, 50 μL; Serum, 50 μL; Supernatant, 100 μL
<10%
300 pg/mL
1 hr. 20 min.
<12%
SDS
Product Certifications
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