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Tocris Bioscience™ FTBMT

Potent and selective GPR52 agonist; orally bioavailable and BBB permeable
$131.20 - $503.00
Specifications
Chemical Name or Material | 4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide |
---|---|
CAS | 1358575-02-6 |
Molecular Formula | C19H16F4N4O |
Formula Weight | 392.35 |
Purity | 98% |
Description
- Potent and selective GPR52 agonist (EC50 = 75 nM, Emax = 122%)
- Selective for GPR52 over a panel of 98 targets including D1, D2, AMPA and NMDA
- Suppresses methamphetamine-induced hyperlocomotion in mice
- Inhibits MK-801 -induced hyperactivity (model for acute psychosis), without causing catalepsy in mice
- Orally bioavailable and brain penetrant
Specifications
4-[3-[[3-Fluoro-5-(trifluoromethyl)phenyl]methyl]-5-methyl-1H-1,2,4-triazol-1-yl]-2-methylbenzamide | |
C19H16F4N4O | |
98% |
1358575-02-6 | |
392.35 |
Safety and Handling
Recommended Storage : Store at -20°C
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