FTO Mouse anti-Human, Clone: OTI4A1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527142
DescriptionRising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Alpha-ketoglutarate-dependent dioxygenase FTO; 11411-; Fat mass and obesity-associated protein; FTO; KIAA1752|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of FTO produced in HEK293T cell|
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