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FTO Mouse anti-Human, Clone: OTI4A1, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527142

Catalog No. PIMA527142


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Description

Description

Rising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
Specifications

Specifications

FTO
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q9C0B1
Alpha-ketoglutarate-dependent dioxygenase FTO; 11411-; Fat mass and obesity-associated protein; FTO; KIAA1752
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
79068
Immunohistochemistry (Paraffin), Western Blot
OTI4A1
Unconjugated
FTO
Liquid
FTO
Full length human recombit protein of FTO produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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