Fumarase Mouse anti-Human, Mouse, Rat, Clone: GT7612, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527746
Positive Control: 293T, A431, HeLa, HepG2, mouse liver, rat liver Predicted Reactivity: Zebrafish (90%), Pig (98%), Chicken (91%), Sheep (99%), Chimpanzee (99%), Bovine (98%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.The protein encoded by Fumarase is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in Fumarase can cause fumarase deficiency and lead to progressive encephalopathy.
|PBS with no preservative|
|P07954, P14408, P97807|
|fumarate hydratase, FH, HLRCC, MCL, MCUL1, LRCC|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|14193, 2271, 24368|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Recombit protein encompassing a sequence within the center region of human Fumarate hydratase. The exact sequence is proprietary.|
|Human, Mouse, Rat|
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