Fumarase Mouse anti-Canine, Human, Rat, Clone: OTI1F10, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA524989
DescriptionThe protein encoded by this gene is an enzymatic component of the tricarboxylic acid cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|fumarate hydratase; HLRCC; LRCC; MCL; MCUL1; fumarase; leiomyomatosis and renal cell cancer; multiple hereditary cutaneous leiomyomata|
|-20° C, Avoid Freeze/Thaw Cycles|
|2271, 24368, 480092|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of FH produced in HEK293T cell|
|Canine, Human, Rat|
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