Tocris™ Furamidine dihydrochloride

Selective PRMT1 inhibitor

Manufacturer: Tocris™ 5202/10

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Catalog No. 52-021-0

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For Research Use Only


    Description Furamidine dihydrochloride
    Quantity 10mg
    Product Type Furamidine dihydrochloride
    Molecular Weight 377.27
    Purity >98

    Selective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4µM). Exhibits selectivity over PRMT5, PRMT6 and CARM1 (IC50 values are 166, 283 and >400µM respectively). Inhibits cell proliferation in leukemia cell lines. Cell-permeable.

    • Chemical Name: 4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride
    • Formula: C18H16N4O.2HCl
    • CAS Number: 55368-40-6
    • Solubility: Soluble to 50mM in water and to 50mM in DMSO
    • Purity: >98

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