Tocris Furamidine dihydrochloride
Selective PRMT1 inhibitor
Manufacturer: Tocris 5202/10
DescriptionSelective protein arginine methyltransferase 1 (PRMT1) inhibitor (IC50 = 9.4µM). Exhibits selectivity over PRMT5, PRMT6 and CARM1 (IC50 values are 166, 283 and >400µM respectively). Inhibits cell proliferation in leukemia cell lines. Cell-permeable.
- Chemical Name: 4,4'-(2,5-Furandiyl)bis-benzenecarboximidamide dihydrochloride
- Formula: C18H16N4O.2HCl
- CAS Number: 55368-40-6
- Solubility: Soluble to 50mM in water and to 50mM in DMSO
- Purity: >98
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