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FZD8 Rabbit anti-Human, Unconjugated, Clone: JB40-16, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA534703

Catalog No. PIMA534703


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Description

Description

Positive Control: Mouse lung tissue lysates, Human kidney tissue, human uterus tissue.

Members of the Frizzled family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Frizzled 8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. Its expression has been reported in brain, heart, kidney, pancreas, and skeletal muscle. ESTs have been isolated from embryo, eye, head/neck, heart, kidney, liver/spleen, pancreas, prostate, and testis libraries, as well as many tumor libraries. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.
Specifications

Specifications

FZD8
JB40-16
Unconjugated
Fzd8
Liquid
Fzd8
Recombinant protein
Protein A
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
1 mg/mL
TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
Q9H461
Frizzled-8; Fz8; Fz-8; Fzd8; hFZ8; HGNC:4046
Rabbit
IgG
100 μL
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Primary
8325
SDS
Documents
Product Certifications
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