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Tocris Bioscience™ FzM1.8

Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness

Specifications

CAS 2204290-85-5
Chemical Name or Material 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid
Molecular Formula C18H14N2O4
Purity 98%
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
69-611-0
View Documents
Tocris Bioscience™
6961/10
10 mg
Each for $183.80
N/A
69-615-0
View Documents
Tocris Bioscience™
6961/50
50 mg
Each for $772.00
N/A
Description

Description

  • Frizzled 4 allosteric agonist (pEC50 = 6.4).
  • Potentiates the β-catenin pathway in the absence of any WNT ligand, by biasing FZD4 signaling toward the FZD4/PI3K axis.
  • Preserves stemness and promotes proliferation of undifferentiated cells.
Specifications

Specifications

2204290-85-5
3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid
C18H14N2O4
98%
SDS
Product Certifications
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