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  5. Tocris Bioscience™ FzM1.8

Tocris Bioscience™ FzM1.8
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Catalog No. p-7182922
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Frizzled 4 allosteric agonist; exhibits biased siginaling; preserves stemness

FzM1.8 is a frizzled 4 allosteric agonist (pEC50 = 6.4). Potentiates the β-catenin pathway in the absence of any WNT ligand, by biasing FZD4 signaling toward the FZD4/PI3K axis. Preserves stemness and promotes proliferation of undifferentiated cells.

Specifications

Chemical Name or Material 3-Hydroxy-5-[[(2-Naphthalenylamino)carbonyl]amino]benzoic acid
CAS 2204290-85-5
Quantity 10 mg
Molecular Formula C18H14N2O4
Purity 98%
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