Please call 1-800-766-7000 to place your order or try our site again later.
GABBR1 Mouse anti-Human, Mouse, Rat, Clone: S93A-49, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527704
DescriptionGamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
|PBS with 50% glycerol and 0.09% sodium azide; pH 7.4|
|Q9UBS5, Q9WV18, Q9Z0U4|
|GABA-B receptor 1, GABA-B-R1, GABR1_Human, Gamma aminobutyric acid receptor 1, GB1, GPRC3A|
|2550, 54393, 81657|
|Immunocytochemistry, Immunofluorescence, Western Blot|
|Fusion protein amino acids 873-977 (cytoplasmic C-terminus) of rat GABA(B)R1|
|Human, Mouse, Rat|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok