GABBR1 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA132248
PA1-32248 detects GABBR1 from human samples. PA1-32248 has been successfully used in Western blot applications. The PA1-32248 immunogen is: N-terminus of GABA BR1 subunit (Proprietary)Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
|DAAP-188P13.3, FLJ92613, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
|N-terminus of GABA BR1 subunit (Proprietary)
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