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GABBR1 Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA132248

Catalog No. PIPA132248

Item Discontinued This item has been discontinued by the supplier and is no longer available. Please reach out to your sales representative.


Description

Description

PA1-32248 detects GABBR1 from human samples. PA1-32248 has been successfully used in Western blot applications. The PA1-32248 immunogen is: N-terminus of GABA BR1 subunit (Proprietary)

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

GABBR1
Polyclonal
GABBR1
DAAP-188P13.3, FLJ92613, GABABR1, GABBR1-3, GB1, GPRC3A, dJ271M21.1.1, dJ271M21.1.2
Rabbit
IgG fraction
RUO
2550
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot
Unconjugated
Q9UBS5
GABBR1
N-terminus of GABA BR1 subunit (Proprietary)
100 μL
Primary
Human
Antibody
IgG
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