GABRA4 Mouse anti-Human, Mouse, Rat, Clone: S398A-34, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527701
DescriptionGamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|P28471, P48169, Q9D6F4|
|GABA A receptor subunit alpha 4, GABRA4, Gamma aminobutyric acid A receptor Alpha 4|
|140675, 14397, 2557|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 410-450 (Cytoplasmic C-terminus) of rat GABA-A-Receptor Alpha 4|
|Human, Mouse, Rat|
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