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GABRA4 Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550036

Catalog No. PA550036


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Description

Description

The antibody detects endogenous levels of total GABRA4 protein.

Gamma-aminobutyric acid is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1. Alternatively spliced transcript variants encoding different isoforms have been found in this gene.
Specifications

Specifications

GABRA4
Polyclonal
Unconjugated
GABRA4
Liquid
GABRA4
Synthesized peptide derived from internal of human GABRA4.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
P48169
Gamma aminobutyric acid receptor alpha 4 subunit
Rabbit
IgG
100 μL
-20°C
Primary
2557
Documents
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