GABRD Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 156231AP
DescriptionGAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA Ralpha1-6, GABAA R beta1-3, GABAA Rgamma1-3, GABAA Rdelta, GABAA Repsilon, GABAA Rrho1 and GABAA Rrho2. The GABAB family is composed of GABAB R1alpha and GABAB R1beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|O14764, P18506, P22933|
|GABAA receptor delta, GABA A receptor delta, GABA(A) receptor subunit delta, GABRD|
|14403, 2563, 29689|
|GABRD Fusion Protein Ag8064|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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