GAD2 Mouse anti-Human, Clone: N-GAD65, Abnova™
Mouse monoclonal antibody raised against partial synthetic peptide of human GAD2.
Manufacturer: Abnova Corporation MAB12482
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq]Sequence: PGSGFWSFGSEDGSGDSEN
|Mouse monoclonal antibody raised against partial synthetic peptide of human GAD2.|
|In PBS (0.09% sodium azide)|
|Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
|Immunohistochemistry (PFA fixed), Immunoprecipitation, Radioimmune Assays, Western Blot|
|Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation Radioimmunoassay Western Blot (1:100-1:1000) The optimal working dilution should be determined by the end user.|
|A synthetic peptide (conjugated with KLH) corresponding to amino acids 4-22 at the N-terminus of human GAD2.|
|Protein G purification|
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