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GAD2 Mouse anti-Human, Clone: N-GAD65, Abnova™

Mouse monoclonal antibody raised against partial synthetic peptide of human GAD2.

Manufacturer:  Abnova Corporation MAB12482

Catalog No. 89-934-184


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Description

Description

This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq]

Sequence: PGSGFWSFGSEDGSGDSEN
Specifications

Specifications

GAD2
N-GAD65
Mouse monoclonal antibody raised against partial synthetic peptide of human GAD2.
In PBS (0.09% sodium azide)
GAD65/MGC161605/MGC161607
Mouse
IgG1
50 ug
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Monoclonal
Human
Immunohistochemistry (PFA fixed), Immunoprecipitation, Radioimmune Assays, Western Blot
Unconjugated
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (5 ug/mL) Immunoprecipitation Radioimmunoassay Western Blot (1:100-1:1000) The optimal working dilution should be determined by the end user.
Liquid
GAD2
A synthetic peptide (conjugated with KLH) corresponding to amino acids 4-22 at the N-terminus of human GAD2.
Protein G purification
RUO
Primary
2572
SDS
Documents
Product Certifications
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