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GAD65 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 217601AP

Catalog No. 50-173-3584


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Description

Description

The antibody is specific to GAD2.

GAD65 (glutamic acid decarboxylase-65) are present in autoimmune disorders such as insulin-dependent (type1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.
Specifications

Specifications

GAD65
0.27 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P48320, Q05329, Q05683
GAD 65, GAD2, GAD65, Glutamate decarboxylase 2
Rabbit
IgG
150 μL
-20°C
Primary
14417, 24380, 2572
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
GAD2
Liquid
Gad2
GAD65 Fusion Protein Ag16251
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Documents
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