GADD34 Mouse anti-Canine, Human, Mouse, Non-human primate, Rat, Clone: OTI3D12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA525874
DescriptionRecruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on ft.Ser-15 ft..
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|Q6IN02, P17564, O75807|
|GADD34, growth arrest and DNA damage-inducible protein GADD34, growth arrest and DNA-damage-inducible 34, myeloid differentiation primary response protein MyD116 homolog, protein phosphatase 1 regulatory subunit 15A, protein phosphatase 1, regulatory (inhibitor) subu|
|-20° C, Avoid Freeze/Thaw Cycles|
|171071, 17872, 23645, 476419, 718350|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Full length human recombit protein of PPP1R15A produced in HEK293T cell|
|Canine, Human, Mouse, Non-human primate, Rat|
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