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GANP Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550416

Catalog No. PA550416


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Description

Description

The antibody detects endogenous levels of total GANP / MCM3AP protein.

The minichromosome maintece protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
Specifications

Specifications

GANP
Polyclonal
Unconjugated
MCM3AP
Liquid
MCM3AP
Fusion protein corresponding to residues near the N terminal of human minichromosome maintece complex component 3 associated protein
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunohistochemistry (Paraffin)
1.1 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
O60318
FLJ44336, FLJ45306, GANP, KIAA0572, MAP80
Rabbit
IgG
100 μL
-20°C
Primary
8888
Documents
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