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GAPDH, Polyclonal, Bethyl Laboratories

Rabbit Polyclonal Antibody

Encompass_Preferred

$123.60 - $291.46

Specifications

Classification Polyclonal
Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen GAPDH
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-155-8104
Encompass_Preferred
View Documents Promotion Details
Bethyl Laboratories, IncSupplier Diversity Partner
A300640AM
100 μl
Each for $291.46
Add to cart
 
50-155-8105
Encompass_Preferred
View Documents Promotion Details
Bethyl Laboratories, IncSupplier Diversity Partner
A300640AT
20 μl
Each for $123.60
Add to cart
 
Description

Description

The recommended shelf life for this product is 1 year from date of receipt. Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, Chicken, Turkey, Sheep, Bovine, Dog, Rabbit, Guinea pig_10141, Pig, Golden

GAPDH (Glyceraldehyde-3-phosphate dehydrogenase) is a catalytic enzyme commonly known to be involved in glycolysis. GAPDH exists as a tetramer of identical 37-kDa subunits and catalyzes the reversible reduction of 1,3-bisphosphoglycerate to glyceraldehyde 3-phosphophate in the presence of NADPH. Apart from playing a key role in glycolysis, GAPDH is ubiquitously expressed and displays other activities unrelated to its glycolytic function. GAPDH is reported to be involved in the processes of DNA replication, DNA repair, nuclear RNA export, membrane fusion and microtubule bundling. Studies provide evidence of GAPDH playing an essential part in gene expression observed in apoptosis and as part of the cellular phenotype of age-related neurodegenerative diseases. Further, GAPDH is involved in other cellular processes ranging from membrane fusion, and neuronal apoptosis in cancer. GAPDH is reported to bind to a variety of other proteins, including the amyloid precursor protein, mutations in which cause some forms of Alzheimer's disease (AD), and the polyglutamine tracts of Huntingtin, the protein product aberrant forms of which are causative of Huntington's disease. Associations between GAPDH, actin and tubulin have also be reported. Since GAPDH is expressed at high levels in most tissues, it is useful as protein loading control in Western Blot analysis.
Specifications

Specifications

Polyclonal
Primary
Unconjugated
Polyclonal
GAPDH
SDS
Product Certifications
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