This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein.
- Theoretical MW (kDa): 84.70
- Preparation method: In vitro wheat germ expression system
- Purification: Glutathione Sepharose 4 fast flow
- Storage buffer: 50mM Tris-HCI, 10mM reduced Glutathione, pH=8.0 in the elution buffer
Best use within three months from the date of receipt of this protein.
ELISA, Western Blotting (Recombinant Protein), Antibody Production, Protein Array
|50mM Tris HCl, 10mM reduced Glutathione, pH 8 in the Elution Buffer|
|Glutathione Sepharose 4 Fast Flow|
|Store at -80°C. Aliquot to avoid repeated freezing and thawing.|
|Antibody Production, Array, Enzyme-linked Immunoabsorbent Assay, Western Blot (Recombinant protein)|
|GBA (Human) Recombinant Protein (P01)|
|In vitro wheat germ expression system|
|12.5% SDS-PAGE Stained with Coomassie Blue.|
|Wheat Germ (in vitro)|
We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.
Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.Ok