GBA Mouse anti-Human, Clone: OTI1D12, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526589
DescriptionGBA encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|GBA1; GCB; GLUC; D-glucosyl-N-acylsphingosine glucohydrolase; acid beta-glucosidase; alglucerase; beta-glucocerebrosidase; glucosylceramidase; imiglucerase; lysosomal glucocerebrosidase|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 40-315 of GBA produced in E.coli|
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