GBP5 Mouse anti-Human, Clone: OTI8B12, liquid, TrueMAB™ 

Mouse Monoclonal Antibody

Manufacturer:  OriGene TA502286

Catalog No. 50-167-3352

Description

The guanylate-binding proteins (GBPs) are a family of interferon-induced GTP-binding proteins function in innate immunity against microbial and viral pathogens. In humans, there are seven GBPs from hGBP1 to hGBP7. Human GBP1 and GBP2 have been shown to exhibit antiviral activity as well as being able to regulate the inhibition of proliferation and invasion of endothelial cells in response to interferon (IFN). GBP5 promotes selective NALP3 inflammasome responses to pathogenic bacteria and soluble but not crystalline inflammasome priming agents.

Specifications

• Antigen: GBP5
• Classification: Monoclonal
• Concentration: 0.15 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q96PP8
• Gene Alias: GBP-5
• Host Species: Mouse
• Isotype: IgG1
• Quantity: 100 μL
• Storage Requirements: -20° C, Avoid Freeze/Thaw Cycles
• Primary or Secondary: Primary
• Gene ID (Entrez): 115362

• Applications: Flow Cytometry, Western Blot
• Clone: OTI8B12
• Conjugate: Unconjugated
• Gene: GBP5
• Format: Liquid
• Gene Symbols: GBP5
• Immunogen: Full length human recombit protein of human GBP5 produced in HEK293T cell.
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Type: Antibody
• Monoclonal or Polyclonal: Monoclonal
• Target Species: Human