Glucagon Receptor Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA550668
The antibody detects endogenous levels of total GCGR / Glucagon Receptor protein.Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
|Synthetic peptide corresponding to a region derived from internal residues of human glucagon receptor|
|Antigen affinity chromatography|
|Human, Mouse, Rat|
|Immunohistochemistry (Paraffin), Western Blot|
|PBS with 50% glycerol and 0.05% sodium azide; pH 7.3|
|P47871, Q61606, P30082|
|14527, 24953, 2642|
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