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Glucagon Receptor Rabbit anti-Human, Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA550668

Catalog No. PA550668


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Description

Description

The antibody detects endogenous levels of total GCGR / Glucagon Receptor protein.

Glucagon receptors are G-protein coupled receptors for glucagon and play a central role in the regulation of blood glucose levels and glucose homeostatsis. It regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Glucagon receptors also play an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G-proteins) and modulates the activity of down-stream effectors.
Specifications

Specifications

Glucagon Receptor
Polyclonal
Unconjugated
GCGR
Liquid
GCGR
Synthetic peptide corresponding to a region derived from internal residues of human glucagon receptor
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
Immunohistochemistry (Paraffin), Western Blot
2.7 mg/mL
PBS with 50% glycerol and 0.05% sodium azide; pH 7.3
P47871, Q61606, P30082
GGR
Rabbit
IgG
100 μL
-20°C
Primary
14527, 24953, 2642
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