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GE Healthcare HiScreen™ Capto™ adhere Multimodal Prepacked Column

For intermediate purification and polishing of monoclonal antibodies after the protein A capture step

Manufacturer:  GE Healthcare 28926981

Catalog No. 45-002-532

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  • Strong multimodal anion exchanger with N-benzyl-n-methyl ethanolamine ligand
  • Offers alternative selectivity compared to traditional anion exchangers
  • In flowthrough mode, removal of leached protein A, aggregates, host cell proteins, nucleic acids and viruses from MAbs is performed
  • Antibodies pass directly through the column while the contaminants remain bound
  • Highly cross-linked agarose matrix
  • Ready-to-use columns for convenient process development optimization
  • Bed height of 10cm is designed to allow method optimization and parameter screening
  • Easily connected in series to achieve 20cm bed height



1M Acetic Acid, 1M NaOH
0.3 in.
HiScreen Capto adhere column
Optimization and parameter screening
3 bar
4° to 30°C
1 x 4.7mL
3.93 in.
N-benzyl-n-methyl Ethanolamine
3 to 12
Highly Cross-linked Agarose
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