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GE Healthcare HiTrap™ Capto™ Core 700 Columns Available on GSA/VA Contract for Federal Government customers only.

HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess medium for intermediate purification and polishing of viruses and other large biomolecules.

Manufacturer:  GE Healthcare 17548151

Catalog No. 45-002-598

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Capto Core 700 is a novel, layered bead chromatography medium consisting of a porous outer layer and ligand-activated core.

  • High capacity and productivity in flowthrough mode.
  • Wide operational window of pH and conductivity.
  • Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
  • The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged.
  • These internalized ligands bind impurities strongly over a wide range of pH and salt concentration.
  • The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.

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1M NaOH, 6M Guanidine Hydrochloride, 30% Isopropanol and 70% Ethanol
0.27 in.
HiTrap Capto Core 700 multimodal column
Intermediate purification and polishing of viruses and other large biomolecules
5 bar
4° to 30°C
5 x 1mL
2 to 14
Highly Cross-linked Agarose
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