GE Healthcare HiTrap Capto Core 700 Columns
HiTrap Capto Core 700 is prepacked with Capto Core 700, a multimodal BioProcess medium for intermediate purification and polishing of viruses and other large biomolecules.
Manufacturer: GE Healthcare 17548151
Capto Core 700 is a novel, layered bead chromatography medium consisting of a porous outer layer and ligand-activated core.
- High capacity and productivity in flowthrough mode.
- Wide operational window of pH and conductivity.
- Prepacked HiTrap columns for easy screening and convenient process development, as well as small scale purification.
- The octylamine ligands found in the core of the beads are multimodal, being both hydrophobic and positively charged.
- These internalized ligands bind impurities strongly over a wide range of pH and salt concentration.
- The pores of the bead outer layer prevent large targets (Mr > 700 000) from binding to the ligands while smaller impurities can enter freely into the beads where they are captured.
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|1M NaOH, 6M Guanidine Hydrochloride, 30% Isopropanol and 70% Ethanol|
|HiTrap Capto Core 700 multimodal column|
|Intermediate purification and polishing of viruses and other large biomolecules|
|4° to 30°C|
|5 x 1mL|
|2 to 14|
|Highly Cross-linked Agarose|
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