GE Healthcare MabSelect™ Chromatography Media Available on GSA/VA Contract for Federal Government customers only.

Protein A affinity medium designed for capturing MAbs from large sample volumes

Manufacturer: GE Healthcare 17519902

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Catalog No. 45-002-978

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    Quantity 200mL
    Storage Requirements 2 to 8°C
    Binding Capacity 30mg Human lgG/mL at 2.4 min. residence time
    Product Type MabSelect media
    For Use With (Application) For industrial appliCatIons and well-established in approved processes
    Flow Rate <500cm/Hour
    Particle Size 85μm
    Height (English) Bed 7.87 in.
    Height (Metric) Bed 20cm
    Includes Certificate of Analysis
    Max. Pressure <200kPa
    Matrix Highly Cross-Linked Agarose
    pH Range 3 to 10
    Ligand Type Recombinant Protein A (E. coli)

    • High-flow agarose matrix allows for high flow velocities at production scale
    • BioProcess medium supported for industrial applications and well-established in approved processes
    • Low non-specific binding resulting in low levels of impurities in the product eluate pool
    • Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity
    • Based on highly cross-linked agarose matrix with recombinant protein A ligand
    • Ligand is engineered to favor oriented coupling and expressed in E. coli and is free of components of mammalian origin
    • Hydrophilic nature of the base matrix ensures low levels of non-specific

    • Average particle size: 85µm (d50V)
    • pH Stability cleaning-in-place (CIP): 2 to 12
    • pH Stability working range: 3 to 10
    • Ligand: recombinant protein A (E.coli)
    • Matrix: highly cross-linked agarose
    • Binding capacity/mL chromatography medium: ~30mg human lgG/mL at 2.4 min. residence time
    • Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm

  • Description & Specifications

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