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GE Healthcare MabSelect™ Chromatography Media Available on GSA/VA Contract for Federal Government customers only.

Protein A affinity medium designed for capturing MAbs from large sample volumes

Manufacturer:  GE Healthcare 17519902

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Catalog No. 45-002-978


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Description

Description

  • High-flow agarose matrix allows for high flow velocities at production scale
  • BioProcess medium supported for industrial applications and well-established in approved processes
  • Low non-specific binding resulting in low levels of impurities in the product eluate pool
  • Oriented coupling of ligand and optimized matrix gives high dynamic binding capacity
  • Based on highly cross-linked agarose matrix with recombinant protein A ligand
  • Ligand is engineered to favor oriented coupling and expressed in E. coli and is free of components of mammalian origin
  • Hydrophilic nature of the base matrix ensures low levels of non-specific

  • Average particle size: 85µm (d50V)
  • pH Stability cleaning-in-place (CIP): 2 to 12
  • pH Stability working range: 3 to 10
  • Ligand: recombinant protein A (E.coli)
  • Matrix: highly cross-linked agarose
  • Binding capacity/mL chromatography medium: ~30mg human lgG/mL at 2.4 min. residence time
  • Pressure/Flow specification: <500cm/hr., <200 kPa, BPG 300, bed height 20cm

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Specifications

Specifications

30 mg Human lgG/mL (at 2.4 min. residence time)
For Industrial AppliCatIons and Well-Established in Approved Processes
20 cm
Recombinant Protein A (E. coli)
<200 kPa
2°C to 8°C
MabSelect media
<500 cm/Hoµr
7.87 in.
Certificate of Analysis
Highly Cross-Linked Agarose
200 mL
85 µm
3 to 10
Documents
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