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GE Healthcare MabSelect Sure™ Chromatography Media

Protein A affinity medium for capturing MAbs at process scale. GE Healthcare MabSelect Sure™ Chromatography Media is used in the commercial manufacture of monoclonal antibodies.

Manufacturer:  GE Healthcare 17543801

Catalog No. 45-002-988


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Description

Description

Has an alkali-tolerant rProteain A ligand designed to enhance protease resistance to produce monoclonal antibodies
  • Withstands rigorous CIP and sanitization procedures with 0.1 to 0.5 M NaOH
  • Design gives enhanced protease resistance resulting in lower ligand leakage
  • Generic elution profile for different monoclonal antibodies enables platform approach to purification
  • High-flow agarose matrix allows the processing of large feed volumes
  • Used in the commercial manufacture of monoclonal antibodies
Specifications

Specifications

30 mg Human lgG/mL (at 2.4 min. residence time)
For Use of Rigorous and Cost-Effective CIP and Sanitization Protocols, Manufacture of Monoclonal Antibodies
20 cm
Alkali-stabilized Protein A-derived (E. coli)
<200 kPa
Stable in aqueous Buffers commonly used in Protein A Chromatography
2°C to 8°C
MabSelect SuRe media
<500 cm/Hoµr
7.87 in.
Certificate of Analysis
Highly Cross-Linked Agarose
25 mL
20% Ethanol
85 µm
3 to 12
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