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GEF-H1 Mouse anti-Human, Mouse, Rat, Clone: GT336, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527803

Catalog No. PIMA527803


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Description

Description

Positive Control: 293T, A431, HeLa, C8D30, BCL-1, Raw264.7, C2C12, Rat-2, *3A6 Predicted Reactivity: Dog (92%), Pig (96%), Bovine (94%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications

Specifications

GEF-H1
Monoclonal
1 mg/ml
PBS with no preservative
Q5FVC2, Q60875, Q92974
DKFZp547L106, DKFZp547P1516, FLJ45440, GEF, GEF-H1, GEFH1, KIAA0651, LFP40, P40, ARHGEF2, microtubule-regulated Rho-GEF, Rho/Rac guanine nucleotide exchange factor 2, proliferating cell nucleolar antigen p40, rho guanine nucleotide exchange factor 2, guanine nucleotide exchange factor H1, Rho/Rac guanine nucleotide exchange factor (GEF) 2
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
16800, 310635, 9181
Immunocytochemistry, Immunofluorescence, Western Blot
GT336
Unconjugated
ARHGEF2
Liquid
Arhgef2
Recombit protein encompassing a sequence within the C-terminus region of human GEF-H1. The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human, Mouse, Rat
Documents
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