GEF-H1 Mouse anti-Human, Clone: OTI5F2, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527124
DescriptionGEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|GEF, GEF-H1, GEFH1, LFP40, P40, Rho/Rac guanine nucleotide exchange factor 2, guanine nucleotide exchange factor H1, microtubule-regulated Rho-GEF, proliferating cell nucleolar antigen p40, rho guanine nucleotide exchange factor 2|
|-20° C, Avoid Freeze/Thaw Cycles|
|Full length human recombit protein of ARHGEF2 produced in HEK293T cell|
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