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GEF-H1 Mouse anti-Human, Clone: OTI5F2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527124

Catalog No. PIMA527124


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Description

Description

GEF-H1 activates Rho GTPases by promoting the exchange of GDP and GTP. Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. GEF-H1 may be involved in epithelial barrier permeability, cell motility and polarization, dendritic spine morphology, antigen presentation, leukemic cell differentiation, cell cycle regulation, innate immune response, and cancer. Alternatively spliced transcript variants encoding different isoforms have been identified.
Specifications

Specifications

GEF-H1
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Q92974
GEF, GEF-H1, GEFH1, LFP40, P40, Rho/Rac guanine nucleotide exchange factor 2, guanine nucleotide exchange factor H1, microtubule-regulated Rho-GEF, proliferating cell nucleolar antigen p40, rho guanine nucleotide exchange factor 2
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
9181
Western Blot
OTI5F2
Unconjugated
ARHGEF2
Liquid
ARHGEF2
Full length human recombit protein of ARHGEF2 produced in HEK293T cell
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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