DescriptionGeltrex LDEV-Free Reduced Growth Factor Basement Membrane Matrix is a soluble form of basement membrane extracted from murine Engelbreth-Holm-Swarm (EHS) tumors and is free of viruses, including lactose dehydrogenase elevating virus (LDEV), sometimes found in this type of preparation. The major components of Geltrex matrix include laminin, collagen IV, entactin, and heparin sulfate proteoglycans. It is ideal for the promotion and maintenance of differentiated phenotypes in a variety of cell cultures including primary epithelial cells, endothelial cells, smooth muscle cells, and human induced pluripotent stem cells (iPSC). Geltrex matrix offers, on average, a 2-fold reduction in several growth factors. As a result, analysis of specific growth factor effects in applications requiring basement membrane extract can be carried out in a controlled and reproducible format.
Key Features of Geltrex LDEV-Free Reduced Growth Factor Basement Membrane Matrix:
Gain Reliability and Consistency in Your hESC Studies
Recent advances in processing EHS tumor cells have resulted in virus free basement membrane extracts. Every lot is tested by RT-PCR methods so you can now have confidence that every lot of Geltrex is virus free. Additionally, our consistent manufacturing process helps ensure a protein concentration with very little variation from lot-to-lot, averaging 15 mg/ml so you can have confidence in every purchase.
Investigate Angiogenesis with Validated Gibco Protocols
There are many applications for Geltrex LDEV-Free reduced growth factor basement membrane matrix, each requiring different thicknesses and concentrations. In general, a protein concentration of >5 mg/ml is used for differentiation studies of primary cells. Geltrex LDEV-Free reduced growth factor basement membrane matrix has been used to develop tube formation assay protocols using Gibco primary cells and specialty media. See this and other angiogenesis assay protocols
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|Cell culture grade|
|–20 to –80°C|
|3D Cell culture (extracellular matrices), mammalian cell culture, primary cell culture, stem cell culture|
|For research use only. Not for use in diagnostic procedures|
|–20 to –80°C|
|Geltrex™ LDEV-free Reduced Growth Factor|
For Research Use Only. Not for use in diagnostic procedures.
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