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GFI1 Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen GFI1
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-3491 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
61554
10 μL
Each for $135.30
Add to cart
 
50-199-3490 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
61553
100 μL
Each for $534.00
Add to cart
 
Description

Description

GFI1 is a nuclear zinc finger (ZF) transcriptional repressor that plays an important role in hematopoiesis and inner ear development, and has been implicated in lymphomagenesis. The Gfi1 protein expression is regulated by the ubiquitin-proteasome system. It is reported that ubiquitin ligase Triad1 interacts with the DNA-binding domain of Gfi-1. Gfi-1 represses transcription by directly binding to the consensus DNA sequence in the promoters of its target genes. Deficiency of Gfi-1 causes neutropenia and an accumulation of granulomonocytic precursor cells that is reminiscent of a myelodysplastic syndrome in mice.
Specifications

Specifications

Polyclonal
Primary
GFI1
Unconjugated
SDS
Product Certifications
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