GFI1 Mouse anti-Human, Clone: OTI6E8, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA526742
DescriptionThis gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal domit severe congenital neutropenia, and also domit nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3|
|GFI-1, SCN2, ZNF163, growth factor independence-1, growth factor independent protein 1, zinc finger protein 163, zinc finger protein Gfi-1|
|-20° C, Avoid Freeze/Thaw Cycles|
|Immunohistochemistry (Paraffin), Western Blot|
|Human recombit protein fragment corresponding to amino acids 1-180 of GFI1 produced in E.coli|
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