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GGT1 Rabbit anti-Mouse, Rat, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA549232

Catalog No. PA549232

This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.


Description

Description

Cleaves the gamma-glutamyl bond of extracellular glutathione (gamma-Glu-Cys-Gly), glutathione conjugates, and other gamma-glutamyl compounds. The metabolism of glutathione releases free glutamate and the dipeptide, cysteinyl-glycine, which is hydrolyzed to cysteine and glycine by dipeptidases. In the presence of high concentrations of dipeptides and some amino acids, can also catalyze a transpeptidation reaction, transferring the gamma-glutamyl moiety to an acceptor amino acid to form a new gamma-glutamyl compound. Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracellular GSH level. It is part of the cell antioxidant defense mechanism.
Specifications

Specifications

Ggt1
Polyclonal
PBS with 0.09% sodium azide
Q60928, P07314
Gamma-glutamyltranspeptidase 1, GGT 1, Gamma-glutamyltransferase 1, Glutathione hydrolase 1, Leukotriene-C4 hydrolase, CD224, Gamma-glutamyltranspeptidase 1 heavy chain, Gamma-glutamyltranspeptidase 1 light chain, Ggt1, Ggt
Rabbit
IgG
400 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
116568, 14598
Western Blot
Unconjugated
Ggt1
Liquid
GGT1
KLH conjugated synthetic peptide between 12-39 amino acids from the N-terminal region of rat Ggt1.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Mouse, Rat
Documents
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