Invitrogen™ GILZ Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA593215

Catalog No. PIPA593215

Description

Immunogen sequence: MDLVKNHLMY AVREEVEILK EQIRELVEKN SQLERENTLL KTLASPEQLE KFQSCLSPEE PAPESPQVPE APGGSAV; Positive Samples: 293T, Mouse spleen; Cellular Location: Cytoplasm, Nucleus.

The TSC22 domain family member 3 protein (TSC22D3) is a leucine zipper protein that functions as a transcriptional regulator. The expression of TSC22D3 is stimulated by glucocorticoids and IL-10 and is thought to play a key role in the anti-inflammatory and immunosuppressive effects of these molecules. TSC22D3 can physically interact with and inhibit the activities of key inflammatory signaling mediators such NF-Kappa-B and AP-1. TSC22D3 functions as a transcriptional co-activator for various nuclear receptors and NF-Kappa-B. It has also been shown to be involved in the differentiation of mesenchymal stem cells towards osteoblasts and bone formation.

Specifications

• Antigen: GILZ
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TSC22D3
• Gene Alias: delta sleep inducing peptide, immunoreactor; delta sleep-inducing peptide immunoreactor; DIP; Dsip1; DSIPI; DSIP-immunoreactive leucine zipper protein; DSIP-immunoreactive peptide; GILZ; glucocorticoid-induced leucine zipper protein; long glucocorticoid-induced leucine zipper protein; Protein DIP; Tilz3; TSC22 domain family 3; TSC22 domain family member 3; TSC22 domain family protein 3; TSC22 domain family, member 3; TSC-22 related protein; TSC22D3; TSC-22-like protein; TSC-22R; TSC22-related inducible leucine zipper 3; TSC-22-related protein; TSC22-related-inducible leucine zipper 3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1831
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.37 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q99576
• Gene Symbols: TSC22D3
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 58-134 of human TSC22D3 (NP_0040802).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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