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GLUD2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 144621AP150UL

Encompass_Preferred

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Catalog No. 50-172-9469


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Description

Description

Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamategated, cation-specific ion channels. Kainate/AMPA receptors co-localize with NMDA receptors in many synapses and consist of seven structurally related subunits, designated GluR-1 to -7, as well as GluR- delta2. The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions. The NMDA receptors consist of five subunits: epsilon1, 2, 3, 4 and one zeta subunit. The zeta subunit is expressed throughout the brainstem whereas the four epsilon subunits display limited distribution. In mice, mutations in the gene encoding GluR- delta2 (GRID2) cause the Lurcher phenotype. The gene encoding human GluR- delta2 maps to chromosome 4q22.
Specifications

Specifications

GLUD2
Polyclonal
Unconjugated
GLUD2
GDH 2, GDH2, GLUD2, GLUDP1, glutamate dehydrogenase 2
Rabbit
Antigen Affinity Chromatography
RUO
14804, 2747, 79220
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.21 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P49448, Q61625, Q63226
GLUD2, Grid2
GLUD2 Fusion Protein Ag5748
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
SDS
Documents
Product Certifications
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