GLUL Mouse anti-Human, Clone: OTI1F4, liquid, TrueMAB
Mouse Monoclonal Antibody
Manufacturer: OriGene TA500700
DescriptionGlutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer ft.s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
|Full length human recombit protein of human GLUL produced in HEK293T cell.|
|Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.02% sodium azide|
|GLNS, GS, PIG43, PIG59|
|-20° C, Avoid Freeze/Thaw Cycles|
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