GluR1 Mouse anti-Human, Mouse, Rat, Clone: S355-1, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527694
DescriptionGluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter, L-glutamate, induces a conformation change that leads to the opening of the cation channel and converts the chemical signal to an electrical impulse. Then, the receptor desensitizes rapidly and enters a transiet inactive state characterized by the presence of a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8 GluR1 shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.4|
|P19490, P23818, P42261|
|AMPA 1, AMPA selective glutamate receptor 1, Glutamate receptor 1, GluA1, GLUH 1, GluR K1, GluRK1, Glr-1, Glur-1, HIPA, Glur1, GluR-A, AI853806, 2900051M01Rik, GluRA, Glr1, MGC13325, GLUH1, GluA1, GLUR1, HBGR1, GLURA, gluR-, GluA1, Glutamate receptor ionotropic AMPA 1, Glutamate receptor ionotropic, Gria 1, HBGR1, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243|
|14799, 2890, 50592|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (PFA fixed), Western Blot|
|Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1|
|Human, Mouse, Rat|
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