GluR3 (extracellular) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5111782

Catalog No. PIPA5111782

Description

Reconstitute antibody with 50 μL of double distilled water (DDW). The reconstituted solution can be stored at 4 degrees C for up to 1 week. For longer periods, small aliquots should be stored at -20 degrees C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Peptide sequence is: (C)EKPFHLN YHVDHLD Homology: Mouse, human, dog amino acid residues are identical.

Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing at this locus results in different isoforms, which may vary in their signal transduction properties.

Specifications

• Antigen: GluR3 (extracellular)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: GRIA3
• Gene Alias: 2900064I19Rik; AMPA-selective glutamate receptor 3; BOS_25163; GluA3; Glur3; GluR-3; Gluralpha3; GLURC; GluR-C; GluR-K3; Glutamate receptor 3; Glutamate receptor ionotropic, AMPA 3; GRIA3; Kiaa4184; MRX94; OTTHUMP00000024262; RP11-349N19.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2892, 29628, 53623
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunomicroscopy, Immunoprecipitation, Western Blot
• Concentration: 0.6 mg/mL
• Formulation: PBS with 1% BSA and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P19492, P42263, Q9Z2W9
• Gene Symbols: GRIA3
• Immunogen: Peptide corresponding to amino acid residues 60-73 of rat GluR3 (Extracellular, N-terminus)
• Quantity: 50 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG