Glut4 Mouse anti-Human, Alexa Fluor 647, Clone: 925932, R&D Systems
Mouse Monoclonal Antibody
Manufacturer: R&D Systems FAB86541R025
DescriptionGlut4 (Glucose Transporter Member 4), also known as SLC2A4, is a 509 aa multi-pass type membrane protein and shares 65% aa identity with mouse Glut4. It is an insulin-regulated glucose transporter. Glut4 is most highly expressed in adipose and striated muscle tissues, but has also been reported in multiple other tissues including the nervous system and breast cancer. Insulin stimulated transport of Glut4 has been shown to be impaired in type 2 diabetes patients. Additionally, inhibition of Glut4 may be useful in reducing proliferation of breast cancer cells.
|Flow Cytometry 5 uL/10^6 cells|
|GLUT-4, GLUT4Glucose transporter type 4, insulin-responsive, insulin-responsive glucose transporter type 4, SLC2A4, solute carrier family 2 (facilitated glucose transporter), member 4, solute carrier family 2, facilitated glucose transporter member 4|
|Mouse myeloma cell line NS0-derived recombinant human Glut4 Met1-Asp509 Accession # P14672|
|Protein A or G purified from hybridoma culture supernatant|
|Alexa Fluor 647|
|Supplied in a saline solution containing BSA and Sodium Azide.|
|Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 degreesC as supplied.|
|Detects human Glut4 in direct ELISAs. Stains human Glut4 transfectants but not irrelevant transfectants in flow cytometry.|
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