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Glutaminase C (GAC) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540134

Catalog No. PA540134


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Description

Description

This antibody specifically recognizes GAC but not the KGA isoform. Recommended positive controls: MDA-MB-231 and cholangiocarcinoma tissue. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Sahai (1983) demonstrated phosphate-activated glutaminase (EC 3.5.1.2) in human platelets. It is the major enzyme yielding glutamate from glutamine. Significance of the enzyme derives from its possible implication in behavior disturbances in which glutamate acts as a neurotransmitter(Prusiner, 1981). High heritability of platelet glutaminase was indicated by studies of Sahai and Vogel (1983) who found an intraclass correlation coefficient of 0.96 for monozygotic twins and 0.53 for dizygotic twins.
Specifications

Specifications

Glutaminase C (GAC)
Polyclonal
Unconjugated
GLS
Liquid
GLS
Recombit protein encompassing a sequence within the C-terminus region of human Glutaminase C.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
0.5 mg/mL
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
O94925, D3Z7P3
glutaminase, GLS1, GAM, GAC, GLS, AAD20, GLS
Rabbit
IgG
100 μL
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
14660, 2744
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