Glutamine Synthetase Mouse anti-Human, Mouse, Rat, Clone: GT1055, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527749
Positive Control: 293T, HeLa, HepG2, U87-MG, SK-N-SH, IMR32, SK-N-AS, mouse brain, mouse eye, rat brain Predicted Reactivity: Xenopus laevis (85%), Dog (97%), Pig (96%), Chicken (88%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (96%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.Glutamine synthase is part of the glutamine synthetase family. Ammonia incorporation in animals occurs through the actions of glutamate dehydrogenase and glutamine synthase. Glutamate plays the central role in mammalian nitrogen flow, serving as both a nitrogen donor and nitrogen acceptor. It also has an important role in controlling metabolic regulations of neurotransmitter glutamate. Because of the multiple functions and importance of GS in cellular metabolism, both catalytic activities and synthesis are highly regulated. The activity of GS is controlled by adenylylation. Its activity is decreased in the cerebral cortex of brains affected by Alzheimer ft.s disease, particularly in the vicinity of senile plaques. It is also decreased under conditions of glucose deprivation.
|PBS with no preservative|
|P09606, P15104, P15105|
|GLNS, GS, PIG59, PIG43, glutamate-ammonia ligase, GLUL|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|14645, 24957, 2752|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)|
|Full length human Glutamine synthetase Recombit protein.|
|Human, Mouse, Rat|
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