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GMPS Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 163761AP

Catalog No. 50-173-0904


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Description

Description

Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription.
Specifications

Specifications

GMPS
0.34 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P49915, Q3THK7, Q4V7C6
Glutamine amidotransferase, GMP synthetase, GMPS
Rabbit
IgG
150 μL
-20°C
Primary
229363, 295088, 8833
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
GMPS
Liquid
Gmps
GMPS Fusion Protein Ag9350
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse, Rat
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