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ABCD2, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ABCD2.

Manufacturer:  Abnova Corporation PAB25454

Catalog No. 89-127-069


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Description

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq

Sequence: CPLSDTLAIKGKVID
Specifications

Specifications

ABCD2
0.5 mg/mL
Goat polyclonal antibody raised against synthetic peptide of ABCD2.
In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
NP_005155.1
ABC39|ALDL1|ALDR|ALDRP|hALDR
Goat
Antigen affinity purification
RUO
Primary
225
ELISA, Western Blot
Unconjugated
ELISA (1:32000) Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
ABCD2
Liquid
ABCD2
A synthetic peptide corresponding to amino acids 460-473 at internal region of human ABCD2.
100 ug
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Polyclonal
Human
SDS
Documents
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