ABCD2, Goat, Polyclonal Antibody, Abnova™

Goat polyclonal antibody raised against synthetic peptide of ABCD2.

Supplier:  Abnova Corporation PAB25454

Catalog No. 89-127-069

Description

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. The function of this peroxisomal membrane protein is unknown; however this protein is speculated to function as a dimerization partner of ABCD1 and/or other peroxisomal ABC transporters. Mutations in this gene have been observed in patients with adrenoleukodystrophy, a severe demyelinating disease. This gene has been identified as a candidate for a modifier gene, accounting for the extreme variation among adrenoleukodystrophy phenotypes. This gene is also a candidate for a complement group of Zellweger syndrome, a genetically heterogeneous disorder of peroxisomal biogenesis. [provided by RefSeq

Sequence: CPLSDTLAIKGKVID

Specifications

• Antigen: ABCD2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:32000) Western Blot (0.5-2 ug/mL) The optimal working dilution should be determined by the end user.
• Gene: ABCD2
• Gene Alias: ABC39/ALDL1/ALDR/ALDRP/hALDR
• Host Species: Goat
• Purification Method: Antigen affinity purification
• Regulatory Status: RUO
• Gene ID (Entrez): 225
• Content And Storage: Store at -20°C.
  Aliquot to avoid repeated freezing and thawing.

• Applications: ELISA, Western Blot
• Concentration: 0.5 mg/mL
• Description: Goat polyclonal antibody raised against synthetic peptide of ABCD2.
• Formulation: In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
• Gene Accession No.: NP_005155.1
• Gene Symbols: ABCD2
• Immunogen: A synthetic peptide corresponding to amino acids 460-473 at internal region of human ABCD2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

For Research Use Only